Mice with increased susceptibility for autoimmune conditions
Ncf1 mutated mice
Mice with a spontaneous mutation in the Ncf1 gene encoding the p47phox subunit of the phagocytic NOX2 complex have been shown to have increased susceptibility to various autoimmune and inflammatory conditions. Redoxis are currently establishing a colony of these mice on B6 background with MHCII class q. These mice will later be used in our services as well as available for purchase (estimated spring 2017).