We can also provide a ex vivo efficacy evaluation tool for initial testing or MoA studies in rats. In this ex vivo modification of the adoptive T cell transfer model, one can evaluate the effect of novel drug candidates on autoreactive cells without initial concerns of bioavailability or formulation.
On demand assays (human PBMC, rat primary cells, mouse primary cells, cell lines)
- Biomarker analysis
- Cell characterization
- Functional assays
- ROS detection assays