Redoxis R&D activities

We value connection with academia and actively engage in research programmes, including exchange of personel with academic institutions, to keep up to date with the current findings and methodology and continuous development of services. We are expanding our portfolio with new models as well as refining the models we are already providing, with the aim of being a reliable and cost efficient provider of preclinical models of autoimmunity and inflammation.

We have a strong academic background in animal models of inflammation and autoimmunity. Redoxis was originally founded as a R&D company with focus on development of small molecules regulating oxidation status of cells for treatment of autoimmune conditions. That project is since May 2016 continued in our subsidiary ProNoxis.

Publication list: 

Hahn et al. NOX2 mediates quiescent handling of dead cell remnants in phagocytes (2019) Redox Biol. 

Source et al. NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence? (2018) Free Radic Biol Med. 

Wallner et al. Correlation and cluster analysis of immunomodulatory drugs based on cytokine profiles (2018) Pharmacol Res.

Wallner et al. Cytokine correlation analysis based on drug perturbation (2017) Cytokine. 

Keinhöfer et al. Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps (2017) JCI Insight.

McBean et al. Redox-based therapeutics in neurodegenerative disease (2017) Br J Pharmacol. 

Tuncel et al. Animal models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in rats (2016) PLoS One.

Guerard et al. The SKG Mutation in ZAP-70 also Confers Arthritis Susceptibility in C57 Black Mouse Strains (2016) Scand J Immune

Winter et al. A Reduction in Intracellular Reactive Oxygen Species Due to a Mutation in NCF4 Promotes Autoimmune Arthritis in Mice (2016) Antioxid Redox Signal

Hultqvist et al. Pharmacological Potential of NOX2 Agonists in Inflammatory Conditions (2015) Antioxid Redox Signal

Kelkka et al. Reactvie oxygen species deficiency induces autoimmunity with type 1 interferon signature (2014) Antioxid Redox Signal