EAE resembles the human disease in many ways. However, based on the heterogeneity of disease course and lesion pathology in MS, it is difficult to model all aspects of MS in one animal model. Thus, the availability of different strains, immunogens and adjuvants is very valuable since it allows for inducing different types of disease and pathologies. For more detailed information on our models, see disease specific information sheets.
Rat EAE models
Mouse EAE models